Background：This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.
仕様
Synonyms：Angiopoietin like 4,Angiopoietin related protein 4,Angiopoietin-like protein 4,Angiopoietin-related protein 4,ANGL4,ANGPT L2,ANGPT L4,ANGPTL2,Angptl4,ARP4,Fasting induced adipose factor,FIAF,HARP,Hepatic angiopoietin related protein,Hepatic fibrinogen/angiopoietin related protein,Hepatic fibrinogen/angiopoietin-related protein,HFARP,NL2,Peroxisome proliferator-activated receptor （PPAR） gamma induced angiopoietin related protein,PGAR,pp1158,PPARG angiopoietin related protein,PSEC0166,TGQTL,UNQ171,Weakly similar to angiopoietin 1 [H.sapiens]
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ANGPTL4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
