Background:The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
仕様
Synonyms:B polypeptide of Sm protein ,COD ,RSMB,Sm B/B',Sm B/Sm B' ,Sm B/SmB' ,Sm protein B/B'',Sm-B/B'',Small nuclear ribonucleoprotein polypeptide B,Small nuclear ribonucleoprotein polypeptide B/B',Small nuclear ribonucleoprotein polypeptides B and B' ,Small nuclear ribonucleoprotein polypeptides B and B1 ,Small nuclear ribonucleoprotein-associated proteins B and B'',SmB,SmB/B'',SmB/Sm B' ,SmB/SmB' ,snRNP B,snRNP-B,snRNPB,SNRPB,SNRPB1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human SNRPB
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):6628
Swissprot:P14678
Isotype:IgG
Research Areas:Epigenetics and Nuclear Signaling, Immunology