Background:The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
仕様
Synonyms:CD 258,CD258,CD258 antigen,Delta transmembrane LIGHT,Herpes virus entry mediator ligand,Herpesvirus entry mediator A,Herpesvirus entry mediator ligand,herpesvirus entry mediator-ligand,HVEM L ,HVEM-L,HVEML,Ligand for herpesvirus entry mediator,LIGHT,LTg,soluble form,TNF14,TNF14,TNFSF 14,Tnfsf14,TNFSF14 protein,TR 2,TR2,Tumor necrosis factor (ligand) superfamily, member 14,Tumor necrosis factor ligand superfamily member 14,Tumor necrosis factor ligand superfamily, member 14,Tumor necrosis factor receptor like 2,tumor necrosis factor receptor-like 2,Tumor necrosis factor superfamily member 14,Tumor necrosis factor superfamily member LIGHT
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human TNFSF14
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.