Background：Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones （H2A, H2B, H3, and H4） form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.
仕様
Synonyms：GL105,H2B,H2B histone family member Q,H2B-GL105,H2B.1,H2B/q,H2B2E,H2BFQ,H2BGL105,H2BQ,HIST2H2BE,Histone 2 H2be,histone cluster 2, H2be,histone H2B GL105,histone H2B type 2 E,Histone H2B type 2-E,histone H2B type 2E,Histone H2B-GL105,Histone H2B.q,histone H2BGL105
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human HIST2H2BE
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：8349
Swissprot：Q16778
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
