Background：The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.
仕様
Synonyms：HID 5,Protein S100 A7,Protein S100-A7,PSOR 1,PSOR1,Psoriasin 1,Psoriasin,Psoriasin1,S100 Calcium binding protein A7,S100 calcium-binding protein A7,S100A7,S100A7c,S10A7
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human S100A7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：IHC1：50 - 1：200
Gene_ID（human）：6278
Swissprot：P31151
Isotype：IgG
Research Areas：Cancer, Signal transduction, Tags ＆ Cell Markers
