Background：Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits： TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
仕様
Synonyms：tnnc1a,Cardiac troponin C,slow skeletal and cardiac muscles,TN-C,TNC,Tnnc1,TNNC1,TNNI3,Troponin C,Troponin C slow,Troponin C1 slow
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human TNNC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
