Background：This gene encodes a GTPase-activating protein （GAP） that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
仕様
Synonyms：ARHGAP 7,ARHGAP7,Deleted in liver cancer 1,Deleted in liver cancer 1 protein,DLC 1,Dlc-1,DLC1,DLC1 Rho GTPase activating protein,FLJ21120,HP,HP protein,KIAA1723,p122 RhoGAP,RHG07,Rho GTPase activating protein 7,Rho GTPase-activating protein 7,Rho type GTPase activating protein 7,Rho-type GTPase-activating protein 7,StAR related lipid transfer （START） domain containing 12,StAR related lipid transfer protein 12,StAR-related lipid transfer protein 12,STARD 12,StARD12,START domain containing protein 12 ,START domain-containing protein 12
Host：Rabbit
Reactivity：Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human DLC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：10395
Swissprot：Q96QB1
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction, Tags ＆ Cell Markers
