Background:This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:Cell cycle checkpoint control protein,Cell cycle checkpoint control protein RAD9A,DNA repair exonuclease rad9 homolog A,hRAD 9,hRAD9,Rad 9,RAD 9A,RAD9 (S pombe) homolog,RAD9 homolog A,RAD9 homolog,Rad9a,RAD9A
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human RAD9A
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.