Background:This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described.
仕様
Synonyms:MGC109416,NR2B3,Nuclear receptor subfamily 2 group B member 3,OTTHUMP00000060418,Retanoic X receptor gamma,Retinoic acid receptor RXR gamma,Retinoic acid receptor RXR-gamma,Retinoid X receptor gamma,RXR G,RXR gamma,RXRC,Rxrg,RXRG,RXRgamma
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human RXRG
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):6258
Swissprot:P48443
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Signal transduction