Background：Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist （types I and II） which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：A I,Al,ARG 1,arg1,ARGI1,Arginase 1,Arginase liver,Arginase type I,Arginase,liver,Arginase-1,Arginase1,Liver type arginase,Liver-type arginase,Type I arginase
Host：Rabbit
Reactivity：Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ARG1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：2000
Gene_ID（human）：383
Swissprot：P05089
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
