Background：This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins （hnRNPs）. The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA （hnRNA）. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants.
仕様
Synonyms：ARE binding protein AUFI type A,AU-rich element RNA-binding protein 1,AUF,AUF1,AUF1A,Heterogeneous nuclear ribonucleoprotein D0,hnRNP D,hnRNP D0,Hnrnpd,hnRNPD0,HNRPD,HNRPD,P37
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human HNRNPD
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000 IHC 1：50 - 1：200
Gene_ID（human）：3184
Swissprot：Q14103
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
