Background：This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
仕様
Synonyms：Cytosolic inhibitor of Nrf2,INrf 2,INrf2,Keap 1,KEAP1,KEAP1,Kelch like ECH associated protein 1,Kelch like family member 19,Kelch like protein 19,Kelch-like ECH-associated protein 1,Kelch-like protein 19,KIAA0132,KLHL 19,KLHL19,MGC10630,MGC1114,MGC20887,MGC4407,MGC9454
Host：Rabbit
Reactivity：Human,Rat
Applications：WB,IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human KEAP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
