Background：The bone morphogenetic protein （BMP） receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine （threonine） kinase receptors： type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
仕様
Synonyms：10q23del,Activin A receptor type II like kinase 3,Activin receptor like kinase 3,Activin receptor-like kinase 3,ACVRLK 3,ACVRLK3,ALK 3,ALK-3,ALK3,BMP type-1A receptor,BMPR 1A,Bmpr,BMPR-1A,Bmpr1a,BMR1A,Bone morphogenetic protein receptor type IA,Bone morphogenetic protein receptor type IA precursor,Bone morphogenetic protein receptor type-1A,BR 1a,BR1a,CD 292,CD292,CD292 antigen,EC 2.7.11.30,Serine threonine protein kinase receptor R5,Serine threonine protein kinase receptor R5 precursor,Serine/threonine-protein kinase receptor R5,SKR 5,SKR5,zBMPR IA,zBMPRIA
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human BMPR1A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：657
Swissprot：P36894
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction, Stem cells
