Background：This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：1 25 @dihydroxyvitamin D3 24 hydroxylase,1 25 dihydroxyvitamin D（3） 24 hydroxylase,1,1,25-dihydroxyvitamin D（3） 24-hydroxylase,mitochondrial,24 OHase,24-OHase,25-dihydroxyvitamin D（3） 24-hydroxylase,CP 24,CP24,CP24A,CYP 24,CYP24,CYP24A1,Cytochrome P450 24A1,Cytochrome P450 24A1 mitochondrial,cytochrome P450 CC24,Cytochrome P450 family 24,Cytochrome P450 family 24 subfamily A member 1,Cytochrome P450 family 24 subfamily A polypeptide 1,Cytochrome P450 subfamily XXIV,Cytochrome P450,subfamily XXIV （vitamin D 24-hydroxylase）,Cytochrome P450-CC24,EC 1.14.13.n4,Exo mitochondrial protein,HCAI,HCINF1,MGC126273,MGC126274,mitochondrial,P450 CC24,Vitamin D 24 hydroxylase,Vitamin D（3） 24 hydroxylase,Vitamin D（3） 24-hydroxylase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human CYP24A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：1591
Swissprot：Q07973
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
