Background:This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms.
仕様
Synonyms:Hepatocellular carcinoma autoantigen p62,IF2B2,IGF 2 mRNA binding protein 2,IGF II mRNA binding protein 2,IGF-II mRNA-binding protein 2,IGF2 mRNA-binding protein 2,Igf2bp2,IMP 2,IMP-2,IMP2,Insulin like growth factor 2 mRNA binding protein 2,Insulin-like growth factor 2 mRNA-binding protein 2,OTTHUMP00000082606,OTTHUMP00000082607,OTTHUMP00000082608,p62,VICKZ 2,VICKZ family member 2,VICKZ2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human IGF2BP2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Dilution:WB1:500 - 1:2000
Gene_ID(human):10644
Swissprot:Q9Y6M1
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Metabolism, Immunology, Signal transduction