Background：This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex （MHC） proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Antigen-presenting glycoprotein CD1d,CD1.1,CD1A,CD1d,CD1D antigen,CD1D antigen d polypeptide,CD1d molecule,CD1D,Cd1d1,differentiation antigen CD1 alpha 3,HMC class I antigen like glycoprotein CD1D,Ly 38,MGC34622,R3,R3G1,T cell surface glycoprotein CD1d,Thymocyte antigen CD1D
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human CD1D
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
