Background:This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
仕様
Synonyms:AHC,AHCH ,AHX,DAX 1,DAX1,Dosage sensitive sex reversal,DSS ,DSS AHC critical region on the X chromosome protein 1,DSS-AHC critical region on the X chromosome protein 1,GTD,HHG,Nr0b1,NR0B1,NROB1,Nuclear hormone receptor,Nuclear receptor 0B1,Nuclear receptor DAX 1,Nuclear receptor DAX-1,Nuclear receptor DAX1,Nuclear receptor subfamily 0 group B member 1,SRXY2
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human NR0B1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:10 - 1:100
Gene_ID(human):190
Swissprot:P51843
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Neuroscience