Background:The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.
仕様
Synonyms:DNA directed DNA polymerase beta,DNA pol beta,DNA polymerase beta,DNA polymerase beta subunit,DPOLB,MGC125976,Pol B,Pol beta,POLB,Polymerase (DNA directed) beta
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human POLB
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:200 - 1:1000 IF1:50 - 1:200
Gene_ID(human):5423
Swissprot:P06746
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling