Background:The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.
仕様
Synonyms:DNA double strand break repair and V(D)J recombination protein XRCC4,DNA repair protein XRCC4,SSMED,X ray repair complementing defective repair in Chinese hamster cells 4,X ray repair cross complementing 4,X ray repair cross complementing protein 4,X-ray repair cross-complementing protein 4,XRCC 4,XRCC4,XRCC4
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human XRCC4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.