Background:The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:beta Granin,betagranin (N-terminal fragment of chromogranin A),catestatin,CgA,CHG A,Chga,chromofungin,Chromogranin A,Chromogranin A parathyroid secretory protein 1,Chromogranin A precursor,ChromograninA,CMGA,ER-37,Pancreastatin,Parastatin,Parathyroid secretory protein 1,Pituitary secretory protein I,Secretory protein I,SP I,SP-I,SP1,SPI,Vasostatin,Vasostatin I,Vasostatin II
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human CHGA
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):1113
Swissprot:P10645
Isotype:IgG
Research Areas:Cancer, Neuroscience, Signal transduction, Tags & Cell Markers