Background：ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain （ITGB2） to form the integrin lymphocyte function-associated antigen-1 （LFA-1）, which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 （intercellular adhesion molecules 1 through 3）, and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Lymphocyte function associated antigen,type 1,alpha subunit,Antigen CD11A （p180）,lymphocyte function associated antigen 1,alpha polypeptide,Antigen CD11A,CD 11a,CD11 antigen-like family member A,CD11a,CD11a antigen,Integrin Alpha L,Integrin alpha-L,Integrin gene promoter,Integrin,alpha L （antigen CD11A （p180）,lymphocyte function associated antigen 1,alpha polypeptide）,ITAL,Itgal,ITGAL protein,Leukocyte adhesion glycoprotein LFA 1 alpha chain,Leukocyte adhesion glycoprotein LFA-1 alpha chain,Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain,Leukocyte function associated molecule 1 alpha chain,Leukocyte function-associated molecule 1 alpha chain,LFA 1 alpha （LFA1A）,LFA 1 alpha,LFA 1,LFA 1A,LFA-1A,LFA1A,Ly15,Ly21,Lymphocyte function associated antigen 1,Lymphocyte Function Associated Antigen Type 1 alpha,lymphocyte function-associated antigen 1,alpha polypeptide,p180
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant Protein of human ITGAL
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：3683
Swissprot：P20701
Isotype：IgG
Research Areas：Cancer, Immunology, Signal transduction, Stem cells
