Background：This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
仕様
Synonyms：C-type lectin domain family 8 member A,CLEC8A,hLOX 1,hLOX-1,Lectin like oxidized LDL receptor 1,Lectin like oxLDL receptor 1,Lectin type oxidized LDL receptor 1,Lectin-like oxidized LDL receptor 1,Lectin-like oxLDL receptor 1,Lectin-type oxidized LDL receptor 1,low density lipoprotein oxidized,receptor 1,LOX-1,LOXIN,Olr1,OLR1,Ox LDL receptor 1,Ox-LDL receptor 1,Oxidised low density lipoprotein （lectin like） receptor 1,Oxidized low density lipoprotein receptor 1,Oxidized low density lipoprotein receptor 1 soluble form,Oxidized low-density lipoprotein receptor 1,SCARE1,Scavenger receptor class E,member 1,SLOX1,soluble form,SR-EI
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human OLR1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
