Background:This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes.
仕様
Synonyms:High mobility group (nonhistone chromosomal) protein isoforms I and Y,High mobility group AT hook 1,High mobility group AT-hook protein 1,High mobility group protein 1,High mobility group protein A1,High mobility group protein HMG-I/HMG-Y,High mobility group protein Ia,High mobility group protein R,HMG R,HMG-I(Y),HMGA1,HMGA1,HMGA1A,HMGIY,MGC12816,MGC4242,MGC4854,Nonhistone chromosomal high mobility group protein HMG I/HMG Y
Host:Rabbit
Reactivity:Human
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:A synthetic peptide of human HMGA1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):3159
Swissprot:P17096
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Microbiology