Background：This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：Glutathione S alkyltransferase A1,Glutathione S aryltransferase A1,Glutathione S transferase 2,Glutathione S transferase A1,Glutathione S transferase alpha 1,Glutathione S transferase Ha subunit 1,Glutathione S-transferase A1,GST class-alpha member 1,GST epsilon,GST HA subunit 1,GST,class alpha,1,GST-epsilon,GST2,GSTA1 1,GSTA1,GSTA1-1,GSTA1,GTH1,HA subunit 1,MGC131939,OTTHUMP00000016611,S （hydroxyalkyl）glutathione lyase A1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human GSTA1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：2938
Swissprot：P08263
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction, Tags ＆ Cell Markers
