Background:This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.
仕様
Synonyms:DNA repair protein complementing XP A cells,DNA repair protein complementing XP-A cells,DNA repair protein complementing XPA cells,Excision repair controlling,Xeroderma pigmentosum 1,Xeroderma pigmentosum complementation group A,Xeroderma pigmentosum group A complementing protein,Xeroderma pigmentosum group A-complementing protein,XP 1,XP1,xpa,XPA,Xpac
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human XPA
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:50 - 1:100
Gene_ID(human):7507
Swissprot:P23025
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling