Background：This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
仕様
Synonyms：A1 140 kDa subunit,A1,A1 P145 Activator 1 large subunit,Activator 1 140 kDa subunit,Activator 1 large subunit,Activator 1 subunit 1,DNA binding Protein PO GA,DNA-binding protein PO-GA,MHC binding factor beta,MHCBFB,PO GA,RECC1,Replication factor C （activator 1） 1,145kDa,Replication factor C 140 kDa subunit,Replication factor C,Replication factor C large subunit,Replication factor C subunit 1,Replication factor C1,RF-C 140 kDa subunit,RFC,RFC1,RFC1,RFC140,RFC140 Replication Factor C 140 kDa subunit
Host：Rabbit
Reactivity：Human
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human RFC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：200
Gene_ID（human）：5981
Swissprot：P35251
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
