Background：This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
仕様
Synonyms：CatD,CATD,Cathepsin D,Cathepsin D heavy chain,CD,Ceroid lipofuscinosis neuronal 10,CLN10,CPSD,ctsd,Epididymis secretory sperm binding protein Li 130P,HEL S 130P,Lysosomal aspartyl peptidase,Lysosomal aspartyl protease,MGC2311
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant Protein of human CTSD
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000
Gene_ID（human）：1509
Swissprot：P07339
Isotype：IgG
Research Areas：Cancer, Cell Biology, Neuroscience, Signal transduction
