Background：The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains： the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
仕様
Synonyms：ANT3,Antithrombin,Antithrombin III,Antithrombin-III,AntithrombinIII,AT 3,AT III,AT3,AT3D,ATIII,Heparin cofactor I,MGC22579,Serine （or cysteine） proteinase inhibitor clade C （antithrombin） member 1,Serine cysteine proteinase inhibitor clade C member 1,Serine proteinase inhibitor clade C member 1,Serpin C1,Serpin family C member 1,Serpin peptidase inhibitor clade C （antithrombin） member 1,SERPINC1,THPH7
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human SERPINC1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
