Background:A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:EC 2.7.1.- ,FLJ12171,FN3K related protein,FN3K-related protein,FN3K-RP,FN3KL,Fn3krp,Fn3krp fructosamine-3-kinase-related protein,FN3X,Fructosamine-3-kinase-related protein,Ketosamine-3-kinase,KT3K,MGC40640,RGD1304570,RP23-293H17.3,Testis secretory sperm binding protein Li 211a
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human FN3KRP
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:200 - 1:2000
Gene_ID(human):79672
Swissprot:Q9HA64
Isotype:IgG
Research Areas:Cell Biology, Metabolism, Signal transduction