Background：The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein （X11L）, inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：amyloid beta （A4） precursor protein binding,family A,member 2 binding protein,Amyloid beta A4 protein binding family A member 2 binding protein,Amyloid beta A4 protein-binding family A member 2-binding protein,APBA2BP,dJ63M2.4,dJ63M2.5,EFCBP3,N terminal EF hand calcium binding protein 3,N-terminal EF-hand calcium-binding protein 3,NECA3,NECAB3,Nek2 interacting protein 1,Nek2-interacting protein 1,Neuronal calcium binding protein 3,Neuronal calcium-binding protein 3,NIP1,STIP3,Synaptotagmin interacting protein 2,SYTIP2,X11L binding protein 51,X11L-binding protein 51,XB51
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human NECAB3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
