Background：This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED （muted homolog） gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
仕様
Synonyms：AIMP 3,AIMP3,Aminoacyl tRNA synthetase complex interacting multifunctional protein 3,Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3,ARS interacting multifunctional protein 3,EEF1E1,Elongation factor p18,Eukaryotic translation elongation factor 1 epsilon 1,Eukaryotic translation elongation factor 1 epsilon-1,Homolog of rat elongation factor p18,MCA3,Multisynthase complex auxiliary component p18,Multisynthetase complex auxiliary component p18,p18,p18 component of aminoacyl tRNA synthetase complex
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human EEF1E1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
