Background：The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology （PH） domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：B2 1,CLM1,CTH 1,CYH1,CYTH1,CYTIP,Cytoadhesin 1,CYTOHESIN 1,Cytohesin-1,D17S811E,FLJ34050,FLJ41900,Homolog of secretory protein SEC7,KIAA4240,mKIAA4240,mSec7 1,OTTHUMP00000196778,OTTHUMP00000196779,PH,PH,SEC7 and coiled-coil domain containing protein 1,Pleckstrin homology Sec7 and coiled/coil domains 1,Pleckstrin homology Sec7 and coiled/coil domains protein 1,Pleckstrin homology,Sec7 and coiled coil domains 1,PSCD1,SEC7 and coiled-coil domain-containing protein 1,Sec7,SEC7 homolog A,SEC7 homolog B2 1,SEC7 homolog B2-1,SEC7,yeast,homolog of,Sec7a
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human CYTH1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
