Background：The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase （PTP） family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II （beta GGT II）, and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.
仕様
Synonyms：BM 008,EC 3.1.3.48,HH 13,HH13,HH7 2,HU PP 1,HUPP 1,HUPP1,OV 1,OV1,phosphatase of regenerating liver 2,PRL 2,PRL2,Protein tyrosine phosphatase 4a2,protein tyrosine phosphatase IVA,protein tyrosine phosphatase IVA2,Protein tyrosine phosphatase of regenerating liver 2,protein tyrosine phosphatase type IVA 2,Protein tyrosine phosphatase type IVA member 2 isoform 1,protein tyrosine phosphatase type IVA,member 2,PTP （CAAXII）,ptp IV1a,ptp IV1b,PTP4A,PTPCAAX2,TP4A2
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human PTP4A2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：200 - 1：2000
Gene_ID（human）：8073
Swissprot：Q12974
Isotype：IgG
Research Areas：Cancer, Cell Biology, Signal transduction
