Background:This gene encodes a member of the glycosyl hydrolase 2 family. The encoded protein localizes to the lysosome where it is the final exoglycosidase in the pathway for N-linked glycoprotein oligosaccharide catabolism. Mutations in this gene are associated with beta-mannosidosis, a lysosomal storage disease that has a wide spectrum of neurological involvement.
仕様
Synonyms:Beta-mannosidase,GC04M103771,Lysosomal beta A mannosidase,Manba,MANBA,Mannanase,Mannase
Host:Rabbit
Reactivity:Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human MANBA
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:200 - 1:2000
Gene_ID(human):4126
Swissprot:O00462
Isotype:IgG
Research Areas:Cancer, Metabolism, Neuroscience, Signal transduction