Background:This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.
仕様
Synonyms:BITH,bithoraxoid like protein ,BLP,cytoplasmic dynein light chain 2A ,DNCL2A,DNLC2A,dynein associated protein HKM23 ,dynein associated protein Km23 ,Dynein light chain 2A, cytoplasmic,dynein, cytoplasmic, light polypeptide 2A ,dynein, light chain, roadblock type 1,HSPC162,Roadblock 1,roadblock domain containing 1 ,Roadblock domain containing protein 1,ROBL/LC7 like 1 ,ROBLD1
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human DYNLRB1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.