Background：This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.
仕様
Synonyms：6030405P19Rik,AI429776,B830038C02Rik,Brain and reproductive organ expressed （TNFRSF1A modulator）,brain and reproductive organ expressed protein,Brain and reproductive organ-expressed protein,BRCA1 A complex subunit BRE,BRCA1-A complex subunit BRE,BRCA1/BRCA2 containing complex subunit 4,BRCA1/BRCA2 containing complex subunit 45,BRCA1/BRCA2-containing complex subunit 45,BRCC4,BRCC45,bre,BRE
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human BRE
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：9577
Swissprot：Q9NXR7
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
