Background：This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix （ECM）. Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
仕様
Synonyms：HSMRK222,K222,K222TA2,Metalloproteinase inhibitor 3,MIG 5 protein,MIG5 protein,Protein MIG 5,Protein MIG-5,SFD,Sorsby fundus dystrophy pseudoinflammatory,TIMP 3,TIMP metallopeptidase inhibitor 3,TIMP-3,TIMP3,TIMP3,Tissue Inhibitor of Metalloproteinase 3,Tissue inhibitor of metalloproteinases 3,Tissue inhibitor of metalloproteinases3
Host：Rabbit
Reactivity：Human,Mouse,Rat,Monkey
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human TIMP3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：200
Gene_ID（human）：7078
Swissprot：P35625
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Neuroscience, Signal transduction
