Background：The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT （silencing mediator for retinoid and thyroid receptors） complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
仕様
Synonyms：EBI,F box like/WD repeat protein TBL1X,F-box-like/WD repeat-containing protein TBL1X,SMAP 55,SMAP55,TBL 1,TBL 1X,TBL1,TBL1X,TBL1X,Transducin （beta） like 1,Transducin （beta） like 1 X linked,Transducin （beta） like 1X linked,Transducin beta like 1 X linked,Transducin beta like 1X,Transducin beta like 1X protein,Transducin beta like protein 1,X linked,Transducin beta-like protein 1X,Transducin-beta-like protein 1,X-linked
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：A synthetic peptide of human TBL1X
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：6907
Swissprot：O60907
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience
