Background:Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:AQP 1,AQP CHIP,AQP-1,AQP1,AQP1,aquaporin 1 (channel-forming integral protein,28kDa,CO blood group),aquaporin 1 (Colton blood group),Aquaporin CHIP,Aquaporin-1,Aquaporin-CHIP,Aquaporin1,Channel forming integral protein 28kDa,Channel like integral membrane protein 28 kDa,CHIP 28,CHIP28,CO,Colton blood group,Growth factor induced delayed early response protein,MGC26324,Urine water channel,Water channel protein CHIP 29,Water channel protein CHIP29,Water channel protein for red blood cells and kidney proximal tubule
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human AQP1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):358
Swissprot:P29972
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction