Background:This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.
仕様
Synonyms:6330415E02Rik,A630020F16,D10Bwg0792e ,Netrin receptor UNC5B,Netrin receptor UNC5B Precursor,p53 regulated receptor for death and life,p53 regulated receptor for death and life protein 1 ,p53-regulated receptor for death and life protein 1,p53RDL1,Protein unc-5 homolog 2,Protein unc-5 homolog B,Protein XUNC 5 ,Transmembrane receptor Unc5H2,Unc 5 homolog 2,Unc 5 homolog B,Unc 5 netrin receptor B,UNC 5B,Unc5 (C.elegans homolog) b,Unc5b,UNC5B,UNC5H2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human UNC5B
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):219699
Swissprot:Q8IZJ1
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Neuroscience