Background：This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes （HDAC）. The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
仕様
Synonyms：AV003220,AW554636,Breast cancer metastasis suppressor 1,Breast cancer metastasis-suppressor 1,BRMS1,BRMS1,DKFZp564A063,MGC95128
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human BRMS1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：25855
Swissprot：Q9HCU9
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
