Background：The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：PKU beta,PKU-beta,serine threonine protein kinase,Serine/threonine protein kinase tousled like 1,Serine/threonine-protein kinase tousled-like 1,SNARE protein kinase SNAK,Tlk1,TLK1,Tousled like kinase 1,Tousled-like kinase 1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human TLK1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：9874
Swissprot：Q9UKI8
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Signal transduction
