Background:This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:CED 12,Ced 12 homolog 1,Ced 12 homolog,CED-12,CED12,Ced12 homolog 1,Ced12 homolog,ELMO 1,ELMO-1,Elmo1,ELMO1,Engulfment and cell motility 1,Engulfment and cell motility protein 1,KIAA0281,MGC126406,Protein ced-12 homolog
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human ELMO1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):9844
Swissprot:Q92556
Isotype:IgG
Research Areas:Cancer, Cell Biology, Metabolism, Signal transduction