Background：The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp （DEAD） motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms：ATP dependent RNA helicase DDX3Y,ATP-dependent RNA helicase DDX3Y,DBY ,DDX3Y,DDX3Y,DEAD （Asp-Glu-Ala-Asp） box polypeptide 3 Y linked ,DEAD box protein 3 Y chromosomal,DEAD box protein 3,DEAD/H （Asp-Glu-Ala-Asp/His） box polypeptide Y chromosome,Y-chromosomal
Host：Rabbit
Reactivity：Human,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human DDX3Y
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide,50％ glycerol,pH7.3.
