Background:This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
仕様
Synonyms:5''-cyclic phosphodiesterase subunit delta,GMP PDE delta,GMP-PDE delta,p17 protein,PDE 6,PDE 6D,PDE D,PDE6,PDE6D,PDE6D,PDED,Phosphodiesterase 6D cGMP specific,Phosphodiesterase 6D cGMP specific rod delta,Protein p17,Retinal rod photoreceptor cGMP phosphodiesterase delta,Retinal rod rhodopsin sensitive cGMP 3' 5' cyclic phosphodiesterase subunit delta,Retinal rod rhodopsin-sensitive cGMP 3''
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human PDE6D
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.