Background：This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t（16;21）（q24;q22） translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
仕様
Synonyms：Cbfa2t3,Ccore binding factor runt domain alpha subunit 2 translocated to 3,ETO2,hMTG16,hMTG16a,hMTG16b,MTG16,MTG16,MTG8 related gene 2,MTG8 related protein MTG16a,MTG8 related protein MTG16b,MTG8-related protein 2,MTGR2,Myeloid translocation gene 8 and 16b,Myeloid translocation gene on chromosome 16 protein,Protein CBFA2T3,Zinc finger MYND domain-containing protein 4,ZMYND4
Host：Rabbit
Reactivity：Human
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human CBFA2T3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：863
Swissprot：O75081
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
