Background：The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette （ABC） transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies （ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White）. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric （X）（q13） and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms：ABC transporter 7 protein,ABC7,Abcb7,ABCB7,ASAT,Atm1p,ATP binding cassette 7,ATP binding cassette sub family B （MDR/TAP） member 7,ATP binding cassette sub family B member 7,ATP binding cassette sub family B member 7 mitochondrial,ATP binding cassette transporter 7,ATP-binding cassette sub-family B member 7,ATP-binding cassette transporter 7,EST140535,MDR7,mitochondrial,Multidrug resistance protein 7,P-glycoprotein 7,PGP7
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human ABCB7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB 1：500 - 1：2000 IHC 1：50 - 1：200
Gene_ID（human）：22
Swissprot：O75027
Isotype：IgG
Research Areas：Metabolism, Signal transduction, Stem cells
