Background：The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：FLJ26580,Imp 8,Imp8,Importin-8,Importin8,IPO 8,IPO8,IPO8,Ran binding protein 8,RAN BP8,Ran-binding protein 8,RANBP 8,RanBP8
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human IPO8
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：10526
Swissprot：O15397
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Signal transduction
