Background：This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif （SAM）. This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms：AZK,Cervical cancer suppressor gene 4 protein,HCCS 4,HCCS-4,HCCS4,Human cervical cancer suppressor gene 4 protein,Leucine zipper and sterile alpha motif containing kinase,Leucine zipper- and sterile alpha motif-containing kinase,Mitogen activated protein kinase kinase kinase MLT,Mitogen-activated protein kinase kinase kinase MLT,Mixed lineage kinase 7,Mixed lineage kinase related kinase,Mixed lineage kinase related kinase MRK beta,Mixed lineage kinase with a leucine zipper and a sterile alpha motif,Mixed lineage kinase-related kinase,MLK 7,MLK like mitogen activated protein triple kinase,MLK related kinase,MLK-like mitogen-activated protein triple kinase,MLK-related kinase,MLK7,Mlklak,MLT,MLTK,MRK,Sterile alpha motif and leucine zipper containing kinase AZK,Sterile alpha motif- and leucine zipper-containing kinase AZK,Zak
Host：Rabbit
Reactivity：Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ZAK
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
