Background:This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:BRCA1-A complex subunit RAP80,Nuclear zinc finger protein RAP80,OTTHUMP00000161441,OTTHUMP00000223372,OTTHUMP00000223374,RAP80,Receptor associated protein 80,Receptor-associated protein 80,Retinoid X receptor interacting protein 110,Retinoid x receptor interacting protein,Retinoid X receptor-interacting protein 110,RIP110,Rxrip110,Ubiquitin interaction motif containing 1,Ubiquitin interaction motif containing protein 1,Ubiquitin interaction motif-containing protein 1,UIMC1,UIMC1,X2HRIP110
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human UIMC1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):51720
Swissprot:Q96RL1
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling